化工社化工社 化学情報印刷レポート · 研究参考用
Cyclopentylacetic acid → N-(cyclopentylacetyl)-L-alanine Iso-butyl Ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cyclopentylacetic acid | HCID 71606 | — |
| 反応物 | 2-Methylpropyl (2S)-2-aminopropanoate hydrochloride | HCID 86584981 | — |
| 生成物 | N-(cyclopentylacetyl)-L-alanine Iso-butyl Ester | HCID 54023872 | — |
反応手順
Following General Procedure B above, and using cyclopentylacetic acid (Aldrich) and L-alanine iso-butyl ester hydrochloride (from Example B above), the title compound was prepared as a solid having a melting point of 62° C.-64° C. The reaction was monitored by tlc on silica gel (Rf=0.37 in 1:3 EtOAc:hexane) and purification was by extraction with Et2O followed by washes with aqueous K2CO3 and aqueous HCl.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06642261B2 |
| 出典データセット | uspto-grants-2003_11 |
| ORD ID | ord-8ba448fad6704f17991aa01c781f970b |
| 出典メモ | uspto-grants-2003_11 |