4-Amino-3-hydroxybenzoic acid → HCID 178498197, compound

HRID 478841Notes

Reaction equation

HRID 478841 reaction equation
[CH3:1][C:2]1[NH:3][N:4]([C:8]2[CH:13]=[CH:12][C:11]([CH3:14])=[CH:10][CH:9]=2)[C:5](=[O:7])[CH:6]=1.[NH2:15][C:16]1[CH:25]=[CH:24][C:19]([C:20]([O:22][CH3:23])=[O:21])=[CH:18][C:17]=1[OH:26].[NH2:27]C1C=CC(C(O)=O)=CC=1O>>[OH:7][C:5]1[N:4]([C:8]2[CH:13]=[CH:12][C:11]([CH3:14])=[CH:10][CH:9]=2)[N:3]=[C:2]([CH3:1])[C:6]=1[N:27]=[N:15][C:16]1[CH:25]=[CH:24][C:19]([C:20]([O:22][CH3:23])=[O:21])=[CH:18][C:17]=1[OH:26]

Participants

4

Reactant 3

HCID 1375664-Amino-3-hydroxybenzoic acidHCID 27368983-Methyl-1-(4-methylphenyl)-1H-pyrazol-5-olHCID 7020619Benzoic acid, 4-amino-3-hydroxy-, methyl ester

Product 1

HCID 178498197HCID 178498197, compound

Procedure

Following the procedure of Example 1, except substituting 1-(3,4-dimethylphenyl)-3-methyl-3-pyrazolin-5-one for 3-methyl-1-(4-methylphenyl)-3-pyrazolin-5-one and methyl 4-amino-3-hydroxybenzoate for 4-amino-3-hydroxybenzoic acid, the title compound was prepared as a red solid (0.059 g, 10%). MS(ES) m/z 367 [M+H].

Sources & evidence

ORD record
ord-94e9d5233e5245018ed53134fc417eef
Source dataset
uspto-grants-2003_11
Patent number
US06642265B1

Reaction notes

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