Ammonia → HCID 178508073, compound

Participants

Reaction Steps

A solution of 0.11 g (0.5 mmol) 5-benzylidene-4-methoxy-3-nitroso-1,5-dihydropyrrol-2-one (prepared by the method of H. Poschenrieder et al (Arch. Pharm. Pharm. Med. Chem. 1998, vol. 331, pp. 389-394) and Stachel et al (J. Heterocycl. Chem. 1980, vol. 17, pp. 1195-1199 and Liebigs Ann. Chem. 1985, pp. 1692-1696)) in methanol was boiled under reflux with 0.25 ml (0.25 mmol) of an aqueous ammonia solution for two minutes. The compound 4-amino-5-benzylidene-3-nitroso-1,5-dihydropyrrol-2-one was obtained in a yield of 45% after recrystallization from methanol. The compound decomposes at 260° C.

Provenance & Evidence