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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 478897Generated: October 31, 2026

4-Fluorophenol → HCID 22325256, compound

https://huagongshe.com/reaction/478897

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorophenolHCID 9732—
Reactant3-Methoxybenzyl chlorideHCID 69994—
ProductHCID 22325256HCID 22325256—

Reaction Steps

Alkylation of 4-fluorophenol with 3-methoxybenzyl chloride according to the procedure described in J. Chem. Soc, 2431 (1958) gave 4-fluoro-2-(3′-methoxybenzyl)phenol. This material was converted to compound 79, as a solid and compound 80, mp 153-155° C., by the procedure similar to that in Example 18 method B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06642268B2
Source datasetuspto-grants-2003_11
ORD IDord-74f621b264e4495082db7e98e7a0b646
Source noteuspto-grants-2003_11