Hydrochloric Acid → HCID 18002813, compound

Participants

Reaction Steps

6-(2-Azidoethanoyl)-1,3-dihydrobenzimidazol-2-one (1.0 g, 4.6 mmol) and Pd—C (5%, 0.3g) in methanol (150 mL) and concentrated HCl (2mL), were subjected to hydrogenation at 25 psi and 27° C. for 1 hour. The catalyst was removed by filtration through a ‘filter aid’ and the solvent removed to give 6-(2-aminoethanoyl)-1,3-dihydrobenzimidazol-2-one hydrochloride (1.01 g, 96%) as a brown solid:

Provenance & Evidence