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HRID478937

反应详情

EQUATION

反应方程式

HRID 478937 的结构方程式

REACTANTS

反应物

2
结构：CCOC(C)=N
HCID65066

Ethanimidic acid, ethyl ester

C4H9NO

结构：NCCCC(=O)O.NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@@H]3O[C@H](CN)[C@H](O)[C@@H](O)[C@H]3N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O
HCID131724201

未命名化合物

PRODUCTS

生成物

2
结构：CCCC(=O)O
HCID264

Butanoic acid

C4H8O2

结构：NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@@H]3O[C@H](CN)[C@H](O)[C@@H](O)[C@H]3N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O
HCID70685100

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

For acetamidylation, the neomycin B/γ-amino butyric acid conjugate obtained in Example 9a above is treated with O-ethyl acetimidate in absolute ethanol for 1-2 days, resulting in acetimidylation of the terminal amino groups. The product is purified by ion exchange chromatography, yielding neomycin B/N-acetamidino butyric acid conjugate 16.

WORKUP

后处理

  1. customresulting in acetimidylation of the terminal amino groups
  2. customThe product is purified by ion exchange chromatography