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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 479153Generated: October 31, 2026

HCID 69557136, compound → HCID 69556741, compound

https://huagongshe.com/reaction/479153

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69557136HCID 69557136—
CatalystPalladiumHCID 23938—
SolventAcetic AcidHCID 176—
SolventMethanolHCID 887—
SolventTetrahydrofuranHCID 8028—
ProductHCID 69556741HCID 6955674195%

Reaction Steps

A suspension of 400 mg of 2Z-ethoxy-3-{2-methyl-4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-acrylic acid ethyl ester and 98 mg of Pd/C (10%) in 8 ml of MeOH, 2 ml of THF and 0.5 ml of AcOH was hydrogenated at 22° C./1 bar overnight. The suspension was filtered, the filtrate evaporated and dried to give 380 mg (95%) of the title compound as colourless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06642389B2
Source datasetuspto-grants-2003_11
ORD IDord-48e1ab7344604d75b4aba3e945916b87
Source noteuspto-grants-2003_11