反应详情

温度

55 °C

Carvedilol (4 g) was dissolved in 180 ml, Hexane/IPA in a ratio 1:1 by heating the mixture under stirring at 55° C. water bath. The solution was allowed to sit at room temperature without stirring for about 15 h, then the resulting crystals were filtered through a buchner funnel and dried in a desiccator (connected to air pump) at room temperature until constant weight to yield Carvedilol Form III.

1. temperatureby heating the mixture
2. customto sit at room temperature
3. stirringwithout stirring for about 15 h
4. filtrationthe resulting crystals were filtered through a buchner funnel
5. customdried in a desiccator (connected to air pump) at room temperature until constant weight