HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 8-Hydroxy-7-quinolinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Methyl 8-hydroxyquinoline-7-carboxylate | HCID 12554536 | — |
| Product | 8-Hydroxy-7-quinolinecarboxamide | HCID 11960580 | — |
Reaction Steps
8-Hydroxy-7-quinolinecarboxylic acid methyl ester [as reported by Eckstein, Z. et al. in Pol. J. Chem. 1979, 53(11), 2373-7 (C.A. 92, 215243s)] is reacted with excess ammonia in a steel bomb for 12-18 hr. The excess ammonia is allowed to evaporate and the residue is crystallized from a suitable solvent to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04727152 |
| Source dataset | uspto-grants-1988_02 |
| ORD ID | ord-a272ef90d6fd48a2baa2dfdab2953f6f |
| Source note | uspto-grants-1988_02 |