Water → HCID 44375456, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of (25R)-26-chloro-4,4-dimethyl-5α-cholesta-8,14-dien-3β-ol (50 mg, 0.1 mmol) and sodium iodide (0.8 g) in acetone (3 mL) were heated at 55° C. in a sealed reaction vessel for 3 days. Addition of water, extraction with diethyl ether and concentration under reduced pressure gave a residue which was crystallised 3 times from hexane to give the title compound (37 mg).

Provenance & Evidence