HCID 57274845, compound → HCID 86584299, compound

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Reaction Steps

Cholest-5-ene-3β,16β-diol (600 mg, 1.4 mmol) in ethyl acetate (15 mL) was hydrogenated at atmospheric pressure over 5% palladium on carbon for 3 days. Removal of catalyst by filtration through Celite and purification of the residue by flash chromatography gave the title compound (190 mg). The 1H-NMR spectrum (CDCl3, d) showed characteristic signals at: 0.81 (s, 3H), 0.86 (s, 3H), 0.89 (s, 3H), 3.55 (m, 1H, H-3), 4.31 (m, 1H, H-16). The 13C-NMR spectrum (CDCl3, d) showed characteristic signals at: 71.7 (C-3), 72.9 (C-8). The mass spectrum showed characteristic peaks at: 404.4 (M+).

Provenance & Evidence