HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 20599275, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 69886665 | HCID 69886665 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 20599275 | HCID 20599275 | 66.6% |
Reaction Steps
A mixture of 4,4-dimethyl-16β-(tert-butyldimethylsilyloxy)cholest-5-en-3-one (40 mg, 0.07 mmol), concentrated HCl (0.2 mL) and ethanol (5 mL) were heated to reflux for 20 hours. Removal of solvent under reduced pressure and recrystallization twice from methanol gave 4,4-dimethylcholest-5-en-16-ol-3-one (20 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06645953B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-a6bebadc88b44d29a4c60525eaabb932 |
| Source note | uspto-grants-2003_11 |