Hydrochloric Acid → HCID 18770423, compound

Participants

Reaction Steps

Concentrated hydrochloric acid (0.050 ml; 0.60 mmol) was added to a solution of the crude crystals of 1,4-bis[[4-[4-(3,4,5-trimethoxyphenyl)benzoyl]-1-piperazinyl]methyl]cyclohexane (118 mg; 0.14 mmol) in ethanol (5 ml) and the reaction mixture was concentrated under reduced pressure. After a process of adding ethanol (10 ml) to the residue and concentrating the mixture under reduced pressure was performed twice, the resultant concentrated residue was recrystallized from chloroform-methanol-diethyl ether to obtain 105 mg (yield: 58%) of the title compound as a pale yellow crystalline powder.

Provenance & Evidence