Hydrochloric Acid → HCID 18770445, compound

Participants

Reaction Steps

Concentrated hydrochloric acid (0.030 ml; 0.36 mmol) was added to a solution in ethanol (5 ml) of the crude crystals (72 mg; 0.090 mmol) of 1,4-bis[[4-[(E,E)-5-(4-chlorophenyl)-2,4-pentadienoyl]-1-piperazinyl]methyl]cyclohexane and the reaction mixture was concentrated under reduced pressure. After a process of adding ethanol (10 ml) to the residue and concentrating the mixture under reduced pressure was performed twice, the resultant concentrated residue was recrystallized from methanol-diethyl ether to obtain 66 mg (yield: 50%) of the title compound as a colorless crystalline powder.

Provenance & Evidence