Hydrochloric Acid → HCID 18770409, compound

Participants

Reaction Steps

Concentrated hydrochloric acid (0.055 ml; 0.66 mmol) was added to a solution of 1,4-bis[[4-[(E)-5-(3,4,5-trimethoxyphenyl)-2-penten-4-ynoyl]-1-piperazinyl]methyl]benzene (127 mg; 0.16 mmol) in ethanol (5 ml) and the reaction mixture was concentrated under reduced pressure. After a process of adding ethanol (10 ml) to the residue and concentrating the mixture under reduced pressure was performed twice, the resultant concentrated residue was recrystallized from methylene chloride-methanol-diethyl ether to obtain the title compound as a pale yellow crystalline powder.

Provenance & Evidence