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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 479474Generated: October 26, 2026

Ethanol, 1-ethoxy-2,2,2-trifluoro- → 4-chloro-N-(2,2,2-trifluoro-1-hydroxyethyl)benzamide

https://huagongshe.com/reaction/479474

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanol, 1-ethoxy-2,2,2-trifluoro-HCID 9897—
Reactant4-ChlorobenzamideHCID 12084—
Product4-chloro-N-(2,2,2-trifluoro-1-hydroxyethyl)benzamideHCID 11322758—

Reaction Steps

Trifluoroacetaldehyde ethyl hemiacetal and 4-chlorobenzamide were processed as described in Example 1 A to provide the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06645968B2
Source datasetuspto-grants-2003_11
ORD IDord-a2922543269140889f4ca098a8885dc4
Source noteuspto-grants-2003_11