L-Isoleucine → HCID 29899505, compound
Reaction equation
[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[C@H:3]([CH2:5][CH3:6])[CH3:4].[C:10]1([CH3:19])[CH:15]=[CH:14][C:13]([C:16](Cl)=[O:17])=[CH:12][CH:11]=1>>[CH3:4][C@H:3]([CH2:5][CH3:6])[C@@H:2]([NH:1][C:16](=[O:17])[C:13]1[CH:14]=[CH:15][C:10]([CH3:19])=[CH:11][CH:12]=1)[C:7]([OH:9])=[O:8]Participants
3
Procedure
(L)-Isoleucine and p-toluoyl chloride were processed as described in Example 26A to provide the desired product.
Sources & evidence
- ORD record
- ord-c9157a86b4ed409d9595a9d8e0593589
- Source dataset
- uspto-grants-2003_11
- Patent number
- US06645968B2
Reaction notes
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