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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 479535Generated: October 25, 2026

p-Toluenesulfonic acid → n-[1-(1h-1,2,3Benzotriazol-1-yl)-2,2-dimethylpropyl]-4-chloro-2-fluorobenzamide

https://huagongshe.com/reaction/479535

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Toluenesulfonic acidHCID 6101—
ReactantPivalaldehydeHCID 12417—
Reactant4-Chloro-2-fluorobenzamideHCID 3721849—
ReactantHCID 178418385HCID 178418385—
Productn-[1-(1h-1,2,3Benzotriazol-1-yl)-2,2-dimethylpropyl]-4-chloro-2-fluorobenzamideHCID 18770717—

Reaction Steps

4-Chloro-2-fluorobenzamide, pivaldehyde, benzotriazole and p-toluenesulfonic acid were processed as described in Example 53A to provide the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06645968B2
Source datasetuspto-grants-2003_11
ORD IDord-18edd09d18bc4420af66589d06713f13
Source noteuspto-grants-2003_11