HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ozone → 5-(Benzyloxy)quinoline-6-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ozone | HCID 24823 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 5-(benzyloxy)-6-[(1E)-prop-1-enyl]quinoline | HCID 23431825 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5-(Benzyloxy)quinoline-6-carbaldehyde | HCID 23431821 | — |
Reaction Steps
Treatment of 5-(benzyloxy)-6-[(1E)-prop-1-enyl]quinoline in methylene chloride with excess ozone at −78° C. followed by addition of diisopropylethylamine, aqueous work-up, and subsequent purification by flash column chromatography provides 5-(benzyloxy)quinoline-6-carbaldehyde.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06700001B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-af7ca252dadf4d2ebcf7ebef43cb0b45 |
| Source note | uspto-grants-2004_03 |