5-Amino-2-fluoropyridine → HCID 178512359, compound

HRID 479555Notes

Reaction equation

[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([F:8])=[N:6][CH:7]=1.[N-:9]([C:12]#[N:13])[C:10]#[N:11].[Na+]>>[C:10]([N:9]=[C:12]([NH2:13])[NH:1][C:2]1[CH:7]=[N:6][C:5]([F:8])=[CH:4][CH:3]=1)#[N:11]

Participants

Reactant 2

HCID 8194405-Amino-2-fluoropyridine

HCID 4350929Sodium dicyanamide

Product 1

HCID 178512359HCID 178512359, compound

Procedure

A solution of 5-amino-2-fluoropyridine and sodium dicyanamide was processed as described in Example 71A to provide the desired product.

Sources & evidence

ORD record: ord-06674cb9f65d479793c059572149fd18
Source dataset: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06645968B2

Reaction notes

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