HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butanol → (2s)-4-[5-(Benzyloxy)quinolin-6-yl]butane-1,2-diol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butanol | HCID 6386 | — |
| Reactant | 5-(Benzyloxy)-6-but-3-enylquinoline | HCID 23431827 | — |
| Reactant | 1-((1R)-((2R,4R,5S)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methoxy)-4-((1R)-((2R,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methoxy)phthalazine | HCID 51003674 | — |
| Solvent | Water | HCID 962 | — |
| Product | (2s)-4-[5-(Benzyloxy)quinolin-6-yl]butane-1,2-diol | HCID 67550968 | — |
Reaction Steps
Addition of 5-(benzyloxy)-6-but-3-enylquinoline to a suspension of AD-mix-α in water:tert-butyl alcohol following the procedure described for Example 1, step 2 gives (2S)-4-[5-(benzyloxy)quinolin-6-yl]butane-1,2-diol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06700001B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-50091c68ecd04f71b58065b5c393fb54 |
| Source note | uspto-grants-2004_03 |