HCID 10666000, compound → HCID 10638514, compound

HRID 479596Notes

Reaction equation

HRID 479596 reaction equation
Cl[C:2]1[CH:3]=[C:4]([CH:23]=[CH:24][CH:25]=1)[CH2:5][C:6]1[N:14]2[C:9]([C:10]([OH:15])=[CH:11][CH:12]=[CH:13]2)=[C:8]([C:16](=[O:20])[C:17]([NH2:19])=[O:18])[C:7]=1[CH2:21]C>CCOC(C)=O.CCCCCC>[CH2:5]([C:6]1[N:14]2[C:9]([C:10]([OH:15])=[CH:11][CH:12]=[CH:13]2)=[C:8]([C:16](=[O:20])[C:17]([NH2:19])=[O:18])[C:7]=1[CH3:21])[C:4]1[CH:23]=[CH:24][CH:25]=[CH:2][CH:3]=1

Participants

3

Reactant 1

HCID 10666000HCID 10666000, compound

Product 1

HCID 10638514HCID 10638514, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

(3-(m-Chlorobenzyl)-2-ethyl-8-hydroxyindolizin-1-yl)glyoxylamide 36h. Mp, 144-146° C. (AcOEt-hexane). 88% Yield.

Sources & evidence

ORD record
ord-73d62b83e7ec491f801bcd3dfa44eed6
Source dataset
uspto-grants-2003_11
Patent number
US06645976B1

Reaction notes

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