HCID 10343336, compound → HCID 10046141, compound

HRID 479597Notes

Reaction equation

HRID 479597 reaction equation
[C:1]([CH2:6][O:7][C:8]1[C:16]2[N:12]([C:13]([CH2:24][C:25]3[CH:30]=[CH:29][CH:28]=[C:27](Cl)[CH:26]=3)=[C:14]([CH2:22]C)[C:15]=2[C:17](=[O:21])[C:18]([NH2:20])=[O:19])[CH:11]=[CH:10][CH:9]=1)([O:3][CH2:4][CH3:5])=[O:2]>CCOC(C)=O.CCCCCC>[CH2:24]([C:13]1[N:12]2[C:16]([C:8]([O:7][CH2:6][C:1]([O:3][CH2:4][CH3:5])=[O:2])=[CH:9][CH:10]=[CH:11]2)=[C:15]([C:17](=[O:21])[C:18]([NH2:20])=[O:19])[C:14]=1[CH3:22])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

Participants

3

Reactant 1

HCID 10343336HCID 10343336, compound

Product 1

HCID 10046141HCID 10046141, compoundYield 73%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

(8-(Carbethoxymethyloxy)-3-(m-chlorobenzyl)-2-ethylindolizin-1-yl)glyoxylamide 37h. Mp, 172-175° C. (AcOEt-hexane). 73% Yield.

Sources & evidence

ORD record
ord-b5dae948cbce468184f94ab1e1e19fad
Source dataset
uspto-grants-2003_11
Patent number
US06645976B1

Reaction notes

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