Methanol → HCID 10596247, compound

HRID 479601Notes

Reaction equation

HRID 479601 reaction equation
[CH2:1]([C:8]1[N:16]2[C:11]([C:12]([NH:17][CH2:18][C:19]([O:21][CH3:22])=[O:20])=[CH:13][CH:14]=[CH:15]2)=[C:10]([C:23](=[O:27])[C:24]([NH2:26])=[O:25])[C:9]=1[CH3:28])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(C1N2C(C(NCC(O)=O)=CC=C2)=C(C(=O)C(N)=O)C=1C)C1C=CC=CC=1.CO>CCOCC>[CH3:22][O:21][C:19]([CH2:18][NH:17][C:12]1[C:11]2[N:16]([C:8]([CH2:1][CH:2]3[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]3)=[C:9]([CH3:28])[C:10]=2[C:23](=[O:27])[C:24]([NH2:26])=[O:25])[CH:15]=[CH:14][CH:13]=1)=[O:20]

Participants

5

Reactant 3

HCID 887MethanolHCID 10571764HCID 10571764, compoundHCID 10832653HCID 10832653, compound

Product 1

HCID 10596247HCID 10596247, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Compound 89a was converted to 90a by the same procedure cited for the preparation of 52 from 51. Mp, 293° C. (dec.) (methanol:ether). 61% Yield.

Sources & evidence

ORD record
ord-65ceac7e6bb44c56a95a3bd0103f82fa
Source dataset
uspto-grants-2003_11
Patent number
US06645976B1

Reaction notes

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