HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 479604Generated: October 29, 2026
Diisopropylethylamine → HCID 10110753, compound
https://huagongshe.com/reaction/479604
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Propanedioic acid, 2-phenyl-, 1-(phenylmethyl) ester | HCID 117278 | — |
| Reactant | Benzenecarboximidamide, 4-amino-, hydrochloride (1:1) | HCID 122765 | — |
| Reactant | O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733286 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 10110753 | HCID 10110753 | — |
Reaction Steps
10 g (37 mmol) phenyl malonic acid monobenzyl ester and 7.7 g (37 mmol) 4-amidino aniline hydrochloride were dissolved in 60 ml DMF and cooled to 0° C. 12.2 g (37 mmol) TOTU and 19 ml (111 mmol) DIPEA were added and the mixture stirred at rt overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06645992B2 |
|---|
| Source dataset | uspto-grants-2003_11 |
|---|
| ORD ID | ord-9e7899bbeb4144e78b9556ab05c3f44c |
|---|
| Source note | uspto-grants-2003_11 |
|---|
