Methyl iodide → HCID 10300073, compound

HRID 479641Notes

Reaction equation

[CH2:1]([C:4]1[CH:30]=[C:29]([O:31][C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)[CH:28]=[CH:27][C:5]=1[O:6][CH2:7][CH2:8][CH2:9][CH2:10][O:11][C:12]1[CH:13]=[C:14]2[C:19](=[CH:20][CH:21]=1)[O:18][CH:17]([C:22]([O:24]CC)=[O:23])[CH2:16][CH2:15]2)[CH2:2][CH3:3].I[CH3:39]>>[CH2:1]([C:4]1[CH:30]=[C:29]([O:31][C:32]2[CH:33]=[CH:34][CH:35]=[CH:36][CH:37]=2)[CH:28]=[CH:27][C:5]=1[O:6][CH2:7][CH2:8][CH2:9][CH2:10][O:11][C:12]1[CH:13]=[C:14]2[C:19](=[CH:20][CH:21]=1)[O:18][C:17]([CH3:39])([C:22]([OH:24])=[O:23])[CH2:16][CH2:15]2)[CH2:2][CH3:3]

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 18772275HCID 18772275, compound

Product 1

HCID 10300073HCID 10300073, compound

Procedure

The title compound was prepared from ethyl 6-(4-(2-propyl-4-phenoxyphenoxy)butoxy)-chromane carboxylate following the procedures described in Example 2, Step A employing iodomethane instead of iodopropane, and subsequently the procedure in Example 1 Step C.

Sources & evidence

ORD record: ord-0a271b7329184635bb85bde0b181b12e
Source dataset: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06645997B2

Reaction notes

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