Methyl iodide → HCID 18772271, compound

HRID 479644Notes

Reaction equation

[Cl:1][C:2]1[CH:27]=[C:26]([O:28][C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH:25]=[CH:24][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][O:8][C:9]1[CH:18]=[C:17]2[C:12]([CH2:13][CH2:14][CH:15]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[O:16]2)=[CH:11][CH:10]=1.I[CH3:36]>>[Cl:1][C:2]1[CH:27]=[C:26]([O:28][C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=2)[CH:25]=[CH:24][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][O:8][C:9]1[CH:18]=[C:17]2[C:12]([CH2:13][CH2:14][C:15]([CH3:36])([C:19]([O:21][CH2:22][CH3:23])=[O:20])[O:16]2)=[CH:11][CH:10]=1

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 18772278HCID 18772278, compound

Product 1

HCID 18772271HCID 18772271, compound

Procedure

The title compound was prepared following the procedure described in Example 2 employing ethyl 7-(3-(2-chloro-4-phenoxyphenoxy)propoxy)-chromane-2-carboxylate (Example 17) instead of ethyl 7-(3-(2-propyl-4-phenoxyphenoxy)propoxy)-chromane-2-carboxylate, and iodomethane instead of iodopropane.

Sources & evidence

ORD record: ord-cfe82de746a342369aa3df691284638e
Source dataset: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06645997B2

Reaction notes

Loading…