3-Methylpiperidine → HCID 18772032, compound

HRID 479665Notes

Reaction equation

HRID 479665 reaction equation
[CH3:1][CH:2]1[CH2:7][CH2:6][CH2:5][NH:4][CH2:3]1.[Br:8][C:9]1[N:14]=[C:13]([CH:15]=O)[CH:12]=[CH:11][CH:10]=1>>[Br:8][C:9]1[CH:10]=[CH:11][CH:12]=[C:13]([CH2:15][N:4]2[CH2:5][CH2:6][CH2:7][CH:2]([CH3:1])[CH2:3]2)[N:14]=1

Participants

3

Reactant 2

HCID 790813-MethylpiperidineHCID 27570096-Bromopyridine-2-carbaldehyde

Product 1

HCID 18772032HCID 18772032, compound

Procedure

16] 3-Methylpiperidine (0.33 mL, 2.8 mmol) was added to a solution of 6-bromo-2-pyridine-carboxaldehyde (350 mg, 1.88 mmol) to give 2-bromo-6-[(3-methylpiperidyl)methyl]pyridine as a white solid.

Sources & evidence

ORD record
ord-2e887bfc0ee34183ab7e04b4d590f1e5
Source dataset
uspto-grants-2003_11
Patent number
US06645990B2

Reaction notes

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