4-Chloroaniline → HCID 9857906, compound

HRID 479724Notes

Reaction equation

[F:1][C:2]1[CH:13]=[CH:12][C:5](/[CH:6]=[CH:7]/[S:8](Cl)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[Cl:14][C:15]1[CH:21]=[CH:20][C:18]([NH2:19])=[CH:17][CH:16]=1>>[F:1][C:2]1[CH:13]=[CH:12][C:5](/[CH:6]=[CH:7]/[S:8]([NH:19][C:18]2[CH:20]=[CH:21][C:15]([Cl:14])=[CH:16][CH:17]=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 78124-Chloroaniline

HCID 12114475315495-38-6

Product 1

HCID 9857906HCID 9857906, compoundYield 81.7%

Procedure

A solution of (E)-4-fluorostyrylsulfonyl chloride (10 mmol) and 4-chloroaniline (10 mmol) was subjected to General Procedure 1, part B. The title compound, melting point 126-128° C, was obtained in 81.7% yield.

Sources & evidence

ORD record: ord-1d85f80ff0984ebaa6ee3342310c75d9
Source dataset: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06646009B2

Reaction notes

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