Diethyl (ethoxymethylene)malonate → HCID 18000191, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2-benzylamino-5-aminopyridine (1.76 g) and diethyl ethoxymethylenemalonate (1.78 mL, 8.82 mmol) was heated at 130° C. for 2 h. While warm, the mixture was evacuated. After cooling, the product was triturated with 2:1 hexanes/ether and collected to give 2.74 g of diethyl (2-benzylamino-5-pyridylaminomethylene)malonate as a gold solid.

Provenance & Evidence