Methanamine, N-methoxy-, hydrochloride (1:1) → 2-Tert-butoxycarbonylamino-n-methoxy-n-methyl succinamic acid benzyl ester

HRID 480237Notes

Reaction equation

HRID 480237 reaction equation
Cl.[CH3:2][NH:3][O:4][CH3:5].[CH2:6]([O:13][C:14](=[O:28])[CH:15]([NH:20][C:21]([O:23][C:24]([CH3:27])([CH3:26])[CH3:25])=[O:22])[CH2:16][C:17]([OH:19])=O)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[CH2:6]([O:13][C:14](=[O:28])[CH:15]([NH:20][C:21]([O:23][C:24]([CH3:27])([CH3:26])[CH3:25])=[O:22])[CH2:16][C:17]([N:3]([O:4][CH3:5])[CH3:2])=[O:19])[C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 81138Methanamine, N-methoxy-, hydrochloride (1:1)HCID 44509514-(Benzyloxy)-3-{[(tert-butoxy)carbonyl]amino}-4-oxobutanoic acid

Product 1

HCID 207010802-Tert-butoxycarbonylamino-n-methoxy-n-methyl succinamic acid benzyl ester

Procedure

This compound was prepared by a method analogous to that of Example 3-part (d) from N,O-Dimethylhydroxylamine hydrochloride and 2-tert-Butoxycarbonylamino-succinic acid 1-benzyl ester.

Sources & evidence

ORD record
ord-5fb173cb1a61415eb056304bbd980063
Source dataset
uspto-grants-2003_11
Patent number
US06649642B2

Reaction notes

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