Heptanenitrile, 7-bromo- → HCID 22246898, compound

Participants

Reaction Steps

In an analogous manner to the procedure described in Step A of Example 1, trans-N-[3-(3,5-dichloro-phenyl)-allyl]-methanesulfonamide (500 mg, 2.45 mmol) was alkylated with 7-bromoheptanenitrile (781 mg; 2.94 mmol) at room temperature over 24 h to provide the title compound of Step A (760 mg). 1H NMR (CDCl3 400 MHz) δ 7.26 (m, 3H), 6.49 (d, 1H), 6.22 (m, 1H), 3.98 (m, 2H), 3.22 (t, 2H), 2.88 (s, 3H), 2.36 (t, 2H), 1.68-1.35 (m, 8H).

Provenance & Evidence