Potassium Iodide → S-Adenosylhomocysteine

HRID 480387Notes

Reaction equation

HRID 480387 reaction equation
Cl.ClC[CH:4](O)[C@H:5]1[O:9][C@@H:8]([N:10]2[C:19]3[N:18]=[CH:17][N:16]=[C:14]([NH2:15])[C:13]=3[N:12]=[CH:11]2)[C@H:7]([OH:20])[C@@H:6]1[OH:21].[NH2:23][C@H:24]([C:28]([OH:30])=[O:29])[CH2:25][CH2:26][SH:27].[I-].[K+]>O>[C@@H:8]1([N:10]2[C:19]3[N:18]=[CH:17][N:16]=[C:14]([NH2:15])[C:13]=3[N:12]=[CH:11]2)[O:9][C@H:5]([CH2:4][S:27][CH2:26][CH2:25][C@@H:24]([C:28]([OH:30])=[O:29])[NH2:23])[C@@H:6]([OH:21])[C@H:7]1[OH:20]

Participants

5

Reactant 3

HCID 4875Potassium IodideHCID 91552HomocysteineHCID 20602943HCID 20602943, compound

Product 1

HCID 439155S-Adenosylhomocysteine

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

condensing 5′-chloromethyl adenosine hydrochloride with L-homocysteine in the presence of water and potassium iodide at 70 to 80° C. to obtain S-adenosyl-L-homocysteine (SAH), and

Sources & evidence

ORD record
ord-f96589ea4540461ba3103fa5a6a95df1
Source dataset
uspto-grants-2003_11
Patent number
US06649753B2

Reaction notes

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