HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 480409Generated: October 25, 2026
Methyl iodide → 2-Amino-4-(3,5-diacetylphenyl)amino-1,6-dimethylpyrimidinium iodide
https://huagongshe.com/reaction/480409
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Cni H1194 | HCID 133109 | — |
| Solvent | Acetonitrile tetrahydrofuran | HCID 22177404 | — |
| Product | 2-Amino-4-(3,5-diacetylphenyl)amino-1,6-dimethylpyrimidinium iodide | HCID 9845352 | — |
Reaction Steps
Compound No. 2, FIG. 1A: A suspension of Compound No. 11 (2-amino-4-(3,5-diacetylphenyl)amino-6-methylpyrimidine) (0.284 g), was suspended in 1:1 acetonitrile-tetrahydrofuran was treated with methyl iodide (2 mL) and heated at 40-45° C. under a reflux condenser for 18 hr. Cooling and filtration gave 0.35 g of 2-amino-4-(3,5-diacetylphenyl)amino-1,6-dimethylpyrimidinium iodide, mp 292° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06649797B2 |
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| Source dataset | uspto-grants-2003_11 |
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| ORD ID | ord-c592da5037114eec80d273c9922a3f21 |
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| Source note | uspto-grants-2003_11 |
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