HRID480447

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1

HCID618233

1-Tritylimidazole-4-carboxaldehyde

C23H18N2O

结构：CC(C)(C)[Si](C)(C)Oc1ccc2cc(Br)ccc2c1

HCID13473083

[(6-Bromonaphthalen-2-yl)oxy](tert-butyl)dimethylsilane

C16H21BrOSi

PRODUCTS

生成物

结构：CC(C)(C)[Si](C)(C)Oc1ccc2cc(C(O)c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)ccc2c1

HCID18769033

未命名化合物

收率 73.2%

PROCEDURE

实验过程

In a similar manner to that described in Reference example 1, the reaction was carried out by using 6-bromo-2-tert-butyldimethylsilyloxynaphthalene (50.0 g) and 4-formyl-1-trityl-1H-imidazole (38.6 g) to give the titled compound (49.8 g) as a colorless powder.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b3a7395b068d4e13b92e558348314e4a
来源数据集: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06649643B1
来源说明: uspto-grants-2003_11

反应 SMILES

Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([O:12][Si:13]([C:16]([CH3:19])([CH3:18])[CH3:17])([CH3:15])[CH3:14])[CH:6]=[CH:5]2.[CH:20]([C:22]1[N:23]=[CH:24][N:25]([C:27]([C:40]2[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=2)([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH:26]=1)=[O:21]>>[Si:13]([O:12][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[CH:3]=[C:2]([CH:20]([C:22]1[N:23]=[CH:24][N:25]([C:27]([C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=3)([C:34]3[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=3)[C:40]3[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=3)[CH:26]=1)[OH:21])[CH:11]=[CH:10]2)([C:16]([CH3:19])([CH3:18])[CH3:17])([CH3:15])[CH3:14]