Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 480481Generated: October 29, 2026

Propylamine → HCID 178457658, compound

https://huagongshe.com/reaction/480481

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropylamineHCID 7852—
Reactant6-(1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl)-2-naphthoic acidHCID 18769101—
Reactantmethyl 6-(1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl)-2-naphthoateHCID 22285069—
ProductHCID 178457658HCID 178457658—

Reaction Steps

In a manner to that described in Example 9-(i), methyl 6-(1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl)-2-naphthoate (2.83 g) was converted to 6-(1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl)-2-naphthoic acid, which was reacted with n-propylamine (0.66 mL) in a similar manner as described in Example 24-(i) to give the titled compound (2.74 g) as a colorless powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06649643B1
Source datasetuspto-grants-2003_11
ORD IDord-bf5f28b640af4ca0a550b88dee969e20
Source noteuspto-grants-2003_11