HCID 18769069, compound → HCID 178458197, compound

Participants

Reaction Steps

A mixture of 6-[1-hydroxy-1-(1-trityl-1H-imidazol-4-yl)-2-propenyl]-N-methyl-2-naphthamide (444 mg) and 10% palladium carbon (50% wet; 100 mg) in ethyl acetate (6 mL) was stirred for 12 h at room temperature under hydrogen atmosphere. The catalyst was filtered off, and the filtrate was concentrated and crystallized from ethyl acetate to give the titled compound (359 mg) as a pale yellow powder.

Provenance & Evidence