Triethylamine → HCID 18764645, compound

Participants

Reaction Steps

This novel compound was prepared as follows: Bromoacetyl bromide (4.25 g; 21 mmol) was added dropwise to a solution of dioctadecylamine (10 g; 19 mmol) and Et3N (2.13 g; 21 mmol) in CHCl3 (400 mL). After 4 h at room temperature the reaction solution was washed with H2O, dried over Na2SO4 and evaporated. The residue was purified by flash chromatography (n-hexane/Et2O=8/2 (v/v) to give the desired product (7.5 g; 11.5 mmol). Yield 61%. K.F.: <0.1%; The 1H-NMR, 13C-NMR, MS and IR spectra were consistent with the postulated structure

Provenance & Evidence