Methyl acetoacetate → HCID 20604583, compound

HRID 480580Notes

Reaction equation

Br[C:2]1[CH:8]=[C:7]([F:9])[CH:6]=[C:5]([O:10][CH3:11])[C:3]=1[NH2:4].[C:12]([O:18][CH3:19])(=[O:17])[CH2:13][C:14]([CH3:16])=O>>[CH3:19][O:18][C:12]([C:13]1[C:2]2[C:3](=[C:5]([O:10][CH3:11])[CH:6]=[C:7]([F:9])[CH:8]=2)[NH:4][C:14]=1[CH3:16])=[O:17]

Participants

Reactant 2

HCID 7757Methyl acetoacetate

HCID 585727442-Bromo-4-fluoro-6-methoxybenzenamine

Product 1

HCID 20604583HCID 20604583, compound

Procedure

The above compound A was prepared from 2-bromo-4-fluoro-6-methoxy aniline and methyl acetoacetate according to the general procedure described above for Example 83, steps D and E. 238.0 (M+H), ret t: 3.64 min (A).

Sources & evidence

ORD record: ord-b984ee45b680407e829c9c903c526382
Source dataset: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06653304B2

Reaction notes

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