HCID 67409937, compound → HCID 18766548, compound

Participants

Reaction Steps

tert-Butyl 2-[3-[2-(ethoxycarbonyl)ethenyl]phenoxy]-2-methylpropionate (39.1 g, 0.12 mol) was dissolved in ethanol. Subsequently, 10% palladium in carbon (3.9 g) was added thereto, the mixture was stirred under hydrogen atmosphere overnight at room temperature. The resultant mixture was subjected to filtration by use of Celite, concentration under reduced pressure, and purification by silica gel chromatography (n-hexane/ethyl acetate=20/1), whereby the target compound was obtained (37.1 g, 94%).

Provenance & Evidence