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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 480906Generated: October 30, 2026

2-(3-Methyl-1,2-oxazol-5-yl)acetic acid → N-[(3-methylisoxazol-5yl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/480906

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Methyl-1,2-oxazol-5-yl)acetic acidHCID 4195532—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3-methylisoxazol-5yl)acetyl]alanine Iso-butyl EsterHCID 15481782—

Reaction Steps

Following General Procedure BI above, and using (3-methyl-isoxazol-5-yl)acetic acid (CAS#19668-85-0) and alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06653303B1
Source datasetuspto-grants-2003_11
ORD IDord-533854864a634450b258c0a008ad9d9f
Source noteuspto-grants-2003_11