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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 481008Generated: October 30, 2026

HCID 18765904, compound → HCID 18765875, compound

https://huagongshe.com/reaction/481008

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 18765904HCID 18765904—
CatalystPalladium hydroxideHCID 9942167—
SolventMethanolHCID 887—
ProductHCID 18765875HCID 18765875—

Reaction Steps

A mixture of dimethyl 4-(2,6-dichlorophenyl)-2-(2-methoxy-2-oxoethyl)-6-[2-(2-nitrophenyl)ethyl]-1,4-dihydro-3,5-pyridinedicarboxylate (3.0 g) and palladium hydroxide, 20 wt % on carbon (300 mg) in MeOH (50 ml) was stirred under hydrogen atmosphere by balloon for 4 hours. Catalyst was removed by filtration and filter cake was washed with CH2Cl2. The combined organic solvent was evaporated to afford a dark green solid (2.61 g192%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06653313B2
Source datasetuspto-grants-2003_11
ORD IDord-f27462b10c2a450fb829985e094a7967
Source noteuspto-grants-2003_11