HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18765904, compound → HCID 18765875, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18765904 | HCID 18765904 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 18765875 | HCID 18765875 | — |
Reaction Steps
A mixture of dimethyl 4-(2,6-dichlorophenyl)-2-(2-methoxy-2-oxoethyl)-6-[2-(2-nitrophenyl)ethyl]-1,4-dihydro-3,5-pyridinedicarboxylate (3.0 g) and palladium hydroxide, 20 wt % on carbon (300 mg) in MeOH (50 ml) was stirred under hydrogen atmosphere by balloon for 4 hours. Catalyst was removed by filtration and filter cake was washed with CH2Cl2. The combined organic solvent was evaporated to afford a dark green solid (2.61 g192%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06653313B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-f27462b10c2a450fb829985e094a7967 |
| Source note | uspto-grants-2003_11 |