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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 481157Generated: November 1, 2026

Ethanol → HCID 18767164, compound

https://huagongshe.com/reaction/481157

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantMethanesulfonic AcidHCID 6395—
ReactantHCID 18767163HCID 18767163—
ProductHCID 18767164HCID 18767164—

Reaction Steps

The racemic N-CBZ-3-phenylisoserine of Formula 6 was then esterified by refluxing in ethanol with methane sulfonic acid to provide the (±)-N-CBZ-3-phenylisoserine ethyl ester (Formula 7) ready for chiral chromatographic separation:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06653501B2
Source datasetuspto-grants-2003_11
ORD IDord-145717e4bee24e138e98b8a305d5d789
Source noteuspto-grants-2003_11