Acetic Anhydride → HCID 10740989, compound

HRID 481290Notes

Reaction equation

[CH2:1]([O:8][C@@H:9]1[C@H:15]([O:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C@H:14]([C:24]([F:27])([F:26])[F:25])[O:13][CH:11]([OH:12])[CH2:10]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:28](OC(=O)C)(=[O:30])[CH3:29]>>[C:28]([O:12][CH:11]1[O:13][C@@H:14]([C:24]([F:27])([F:26])[F:25])[C@@H:15]([O:16][CH2:17][C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)[C@@H:9]([O:8][CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH2:10]1)(=[O:30])[CH3:29]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 10714910HCID 10714910, compound

Product 1

HCID 10740989HCID 10740989, compound

Procedure

Step (9'): The 1-hydroxyl group of Compound 74 is then acetylated with acetic anhydride to produce 1-O-acetyl-3,4-di-O-benzyl-2,6-dideoxy-6,6,6-trifluoro-L-lyxo-hexopyranose [Compound 75] of the formula ##STR115##

Sources & evidence

ORD record: ord-2d4d33a0a57d45b2be80152ad3101aa4
Source dataset: uspto-grants-1998_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05789386

Reaction notes

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