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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 481397Generated: October 26, 2026

1,4-Dichlorobutane → 1-Thiophen-2-ylcyclopentane carboxylic acid ethyl ester

https://huagongshe.com/reaction/481397

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DichlorobutaneHCID 8059—
ReactantEthyl 2-thienylacetateHCID 93657—
Product1-Thiophen-2-ylcyclopentane carboxylic acid ethyl esterHCID 57114965—

Reaction Steps

Thiophen-2-yl acetic acid ethyl ester (1) was dialkylated as described in Example 1, Step 1, using 1,4-dichlorobutane to obtain the title compound (31).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05789415
Source datasetuspto-grants-1998_08
ORD IDord-22c4714e03d44172a93cec11c1824e4d
Source noteuspto-grants-1998_08