1,4-Dichlorobutane → 1-(5-Methylpyridin-2-yl)cyclopentane carboxylic acid ethyl ester

HRID 481401Notes

Reaction equation

HRID 481401 reaction equation
[CH2:1]([O:3][C:4](=[O:13])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([CH3:12])=[CH:8][N:7]=1)[CH3:2].Cl[CH2:15][CH2:16][CH2:17][CH2:18]Cl>>[CH2:1]([O:3][C:4]([C:5]1([C:6]2[CH:11]=[CH:10][C:9]([CH3:12])=[CH:8][N:7]=2)[CH2:18][CH2:17][CH2:16][CH2:15]1)=[O:13])[CH3:2]

Participants

3

Reactant 2

HCID 80591,4-DichlorobutaneHCID 571749Ethyl 2-(5-methylpyridin-2-yl)acetate2×

Product 1

HCID 572450121-(5-Methylpyridin-2-yl)cyclopentane carboxylic acid ethyl ester

Procedure

The product of Step 1, above (43), was dialkylated as described in Example 1, Step 1, using 1,4-dichlorobutane to obtain the title compound (44).

Sources & evidence

ORD record
ord-d310e47a563d4fcfb30a8a6fe056be77
Source dataset
uspto-grants-1998_08
Patent number
US05789415

Reaction notes

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