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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 481403Generated: October 25, 2026

2-Cyclopropyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine → 1-[5-(2-Cyclopropyl-5,7-dimethylimidazo[4,5-b]pyridin-3-ylmethyl)pyridin-2-yl]cyclopentane carboxylic acid ethyl ester

https://huagongshe.com/reaction/481403

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Cyclopropyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridineHCID 10313440—
Reactant1-(5-Bromomethylpyridin-2-yl)cyclopentanecarboxlic acid ethyl esterHCID 70103586—
Product1-[5-(2-Cyclopropyl-5,7-dimethylimidazo[4,5-b]pyridin-3-ylmethyl)pyridin-2-yl]cyclopentane carboxylic acid ethyl esterHCID 70086925—

Reaction Steps

The product of Example 10, Step 3, above (45), was alkylated as described in Example 1, Step 5, using 2-cyclopropyl-5,7-dimethylimidazo[4,5-b]pyridine (13) to produce the title compound (48).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05789415
Source datasetuspto-grants-1998_08
ORD IDord-d9823b0750f84d649baf30be4e65a122
Source noteuspto-grants-1998_08