2,6-Dimethyl-8-ethyl-1-deazapurine → HCID 67667094, compound

HRID 481414Notes

Reaction equation

HRID 481414 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([C:11]2[O:12][C:13]3[CH:20]=[CH:19][C:18]([CH2:21]Br)=[CH:17][C:14]=3[C:15]=2[Br:16])[CH2:10][CH2:9][CH2:8][CH2:7]1)=[O:5])[CH3:2].[CH2:23]([C:25]1[NH:26][C:27]2[C:28]([N:35]=1)=[N:29][C:30]([CH3:34])=[CH:31][C:32]=2[CH3:33])[CH3:24]>>[CH2:1]([O:3][C:4]([C:6]1([C:11]2[O:12][C:13]3[CH:20]=[CH:19][C:18]([CH2:21][N:35]4[C:28]5=[N:29][C:30]([CH3:34])=[CH:31][C:32]([CH3:33])=[C:27]5[N:26]=[C:25]4[CH2:23][CH3:24])=[CH:17][C:14]=3[C:15]=2[Br:16])[CH2:10][CH2:9][CH2:8][CH2:7]1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 98153742,6-Dimethyl-8-ethyl-1-deazapurineHCID 57267099HCID 57267099, compound2×

Product 1

HCID 67667094HCID 67667094, compound

Procedure

The product of Step 6, above (60), was alkylated as described in Example 12, Step 3 using 2-ethyl-5,7-dimethylimidazo[4,5-b]pyridine (7) to obtain the title compound (61).

Sources & evidence

ORD record
ord-1cb6d4d955da4a4ca1e93ce251102963
Source dataset
uspto-grants-1998_08
Patent number
US05789415

Reaction notes

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