HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(5-Chloromethylthiophen-2-yl)-cyclopent-3-ene carboxylic acid ethyl ester → 2-butyl-5-chloro-3-[5-(1-ethoxycarbonylcyclopent-3-enyl)thiophen-2-ylmethyl]-3H-imidazole-4-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(5-Chloromethylthiophen-2-yl)-cyclopent-3-ene carboxylic acid ethyl ester | HCID 54533137 | — |
| Reactant | HCID 178441690 | HCID 178441690 | — |
| Product | 2-butyl-5-chloro-3-[5-(1-ethoxycarbonylcyclopent-3-enyl)thiophen-2-ylmethyl]-3H-imidazole-4-carboxylic acid ethyl ester | HCID 70085190 | — |
Reaction Steps
Alkylation was carried out on 1-(5-chloromethylthiophen-2-yl)cyclopent-3-ene carboxylic acid ethyl ester (5) as described in Example 1, Step 5, using 2-butyl-5-chloro-3H-imidazole-4-carboxylic acid ethyl ester (69) to yield the title compound (71).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05789415 |
| Source dataset | uspto-grants-1998_08 |
| ORD ID | ord-95653f53fe8b4cabb19bdf4e1fcf8497 |
| Source note | uspto-grants-1998_08 |