(2S,3S)-3-Amino-1-tert-butoxycarbonyl-2-phenylpiperidine → (2S,3S)-1-tert-Butoxycarbonyl-3-(2-methoxy-5-(1,1-dimethyl-2-propynyl)benzyl)amino-2-phenylpiperidine

HRID 481501Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:8]([C:11]([CH3:15])([CH3:14])[C:12]#[CH:13])=[CH:7][C:4]=1[CH:5]=O.[NH2:16][C@H:17]1[CH2:22][CH2:21][CH2:20][N:19]([C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24])[C@H:18]1[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1.C(OC(N1CCC[C@H](NCC2C=C(C(C#N)C)C=CC=2OC)[C@@H]1C1C=CC=CC=1)=O)(C)(C)C>>[C:26]([O:25][C:23]([N:19]1[CH2:20][CH2:21][CH2:22][C@H:17]([NH:16][CH2:5][C:4]2[CH:7]=[C:8]([C:11]([CH3:15])([CH3:14])[C:12]#[CH:13])[CH:9]=[CH:10][C:3]=2[O:2][CH3:1])[C@@H:18]1[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)=[O:24])([CH3:29])([CH3:27])[CH3:28]